Bertie was a laboratory mouse made with Hybrid technology, with its brain and possibly other organs transplanted into an endoskeleton as a test subject for further human experiments under Dr. Serena Kogan and her division from Cyberdyne Systems. It was the first successful transplant of a living organic brain into a housing endoskeleton based on developing Terminator technology.
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In addition to Bertie, Dr. Kogan also used chimpanzees as test subjects for Hybrid technology.[1]